Mathematical strategies
For the following analyses, “any HPV” means seropositivity otherwise DNA positivity for at least one of the following Hr-HPV types: 16, 18, 30, 33, thirty five, forty five, 52, and you may 58.
Any, type-specific and age-specific ( < 20,>=61 years) HR-HPV seroprevalence (at baseline and follow-up), seropersistence, seroclearance and seroconversion (at follow-up) were assessed. Seropersistence was defined as the number of women who were seropositive at baseline and follow-up among all women who were seropositive at baseline. Seroclearance was the number of women who were seropositive at baseline and seronegative at follow-up among all those seropositive at baseline.
Standard seropositivity is compared with concurrent cervical DNA positivity to assess concordance, that will only be tested during the sort of-certain top, just like the women can be tend to infected that have numerous variety of HPV and you will the fresh concordance updates might be more https://getbride.org/pt/mulheres-espanholas-quentes/ for each type. To get over including restrict, analyses was in fact performed at the genotype height using generalized estimating formula (GEE) models you to account for the possible lack of freedom between multiple findings throughout the same lady [twenty two, 23].
Univariable and multivariable GEE models were performed to identify predictors of HR-HPV seroprevalence at baseline. Risk estimates were adjusted by potential risk factors for HPV seropositivity: age at baseline, marital status, education level, number of children, age at first sexual intercourse, lifetime number of sexual partners, high-risk sexual partner (who engaged in extra-relationship sexual activity), history of sexually transmitted disease, hormonal contraception, smoking, condom use and cervical HR-HPV DNA infection.